Patients should receive prolonged antibiotic therapy with a drug that can treat infections of the brain and central nervous system. If symptoms reappear during therapy, patients may require a change in their antibiotic regimen.

Relapses can occur after therapy has been completed, requiring close patient monitoring.

Patients who experience nutritional deficiencies caused by the malabsorption will receive treatment with appropriate dietary supplements.

• Nutritional deficiencies
• Weight loss
• Reappearance of symptoms, suggesting drug resistance

Call your health care provider if you have persistent abdominal pain and diarrhea.

If you are being treated for Whipple's disease, call your health care provider if symptoms worsen or do not improve, if symptoms reappear, or if new symptoms develop.