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Drug-induced hypothyroidism

Overview Symptoms Treatment Prevention
Treatment:

The drug causing the hypothyroidism may be discontinued if possible. However, do not stop taking prescribed medications without first consulting your healthcare provider, as some may cause unpleasant or even life-threatening reactions if not tapered slowly or replaced appropriately.


Levothyroxine, a thyroid replacement hormone, is the most commonly used medication to treat this condition. The dose is adjusted to normalize TSH. After replacement therapy has begun, report symptoms of increased thyroid activity (hyperthyroidism) -- restlessness, rapid weight loss or sweating if they occur.

A high-fiber, low-calorie diet and moderate activity can help relieve constipation and promote weight loss if a peroid of lowered thyroid activity has lead to weight gain.

Expectations (prognosis):
With early treatment, return to the normal state is usual. However, relapses will occur if the medication is not continued. Myxedema coma can result in death.
Complications:
Myxedema coma, the most severe form of hypothyroidism, is rare. It can be caused by an infection, illness, exposure to cold, or certain medications. Symptoms and signs of myxedema coma include unresponsiveness to stimulation (decreased consciousness), decreased breathing, low blood pressure, low blood sugar, and below-normal body temperature.

Other complications are heart disease, infertility, miscarriage in pregnant women, and pituitary tumors (extremely rare).
Calling your health care provider:
Call your health care provider if signs of myxedema are present; or if chest pain, rapid heartbeat, or infection occur.
Endocrine glands
Endocrine glands
Thyroid gland
Thyroid gland
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