• Sweating
• Tremor
• Rapid heart rate
• Anxiety
• Hunger
• Dizziness
• Headache
• Clouding of vision
• Confusion
• Behavioral changes
• Convulsions
• Loss of consciousness
• Skin rash that migrates on the face, abdomen, perineum, buttocks, or lower extremities
  • May be crusty and scaly
  • May have raised lesions filled with clear fluid or pus
• Inflamed mouth and tongue
• Weight loss
• Weight gain (unintentional)
• Peptic ulcer pain
• Vomiting blood
• Diarrhea
• Abdominal pain

Note: The symptoms depend upon the type of tumor and the hormone produced.

The type of tests performed may vary depending upon the symptoms associated with the condition. Some of the following abnormalities may be detected on testing:

• an abdominal CT scan may reveal a pancreatic tumor (sometimes the tumor may be too small to see with a CT scan)
• MRI of abdomen to show pancreatic tumor (MRI can sometimes see smaller tumors than those seen with a CT scan)
• abnormal glucose tolerance test
• low fasting glucose level
• elevated serum insulin C-peptide
• elevated serum insulin level
• increased gastrin level
• positive secretin stimulation test for pancreas
• elevated fasting glucose level
• elevated serum glucagon level
• abdominal ultrasound
• endoscopic ultrasound
• intraductal endoscopic ultrasound
• occasionally, the diagnosis and treatment (surgical removal) requires exploratory surgery, during which the surgeon feels the pancreas and may use ultrasound probes