| ENCYCLOPEDIA INDEX |
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Injury Disease Nutrition Poison Symptoms Surgery Test |
| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z |
Pagets disease |
| Overview Symptoms Treatment Prevention |
| Alternative Names: |
| Osteitis deformans |
| Treatment: |
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Drug therapy is aimed at suppressing bone breakdown. Currently, there are several classes of medications that inhibit bone resorption that are used in the treatment of Paget's disease. These include: bisphosphonates, calcitonin, and plicamycin. The biphosphonates are the first-line treatment and include the following medications: etidronate (Didronel), alendronate (Fosamax), pamidronate (Aredia), tiludronate (Skelid), and risedronate (Actonel). The Calcitonin class includes intranasal (Miacalcin) and subcutaneous (Calcimar) forms. Plicamycin (Mitrhracin) may also be prescribed. Analgesics or nonsteroidal anti-inflammatory medications (NSAIDS) may be given for pain. |
| Support Groups: |
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Paget Foundation |
| Expectations (prognosis): |
| Disease activity and symptoms can generally be controlled with current medications. Malignant changes of bone occur in less than 1% of people affected. |
| Complications: |
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| Calling your health care provider: |
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Call for an appointment with your health care provider if symptoms of Paget's disease develop. |
X-ray |
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