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ENCYCLOPEDIA INDEX
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Systemic sclerosis (scleroderma)

Overview Symptoms Treatment Prevention
Alternative Names:
CREST syndrome; Progressive systemic sclerosis; Scleroderma
Symptoms:
  • blanching, blueness, or redness of fingers and toes in response to heat and cold (Raynaud's phenomenon)
  • pain, stiffness, and swelling of fingers and joints
  • skin thickening and shiny hands and forearm
  • skin is hard
  • tight and mask-like facial skin
  • ulcerations on fingertips or toes
  • esophageal reflux or heartburn
  • difficulty swallowing
  • bloating after meals
  • weight loss
  • diarrhea
  • constipation
  • shortness of breath
Additional symptoms that may be associated with this disease:
  • wrist pain
  • wheezing
  • skin, abnormally dark or light
  • joint pain
  • hair loss
  • eye burning, itching and discharge
Signs and tests:
Examination of the skin may show tightness, thickening, and hardening.
Raynaud's phenomenon
Raynaud's phenomenon
CREST syndrome
CREST syndrome
Sclerodactyly
Sclerodactyly
Telangiectasia
Telangiectasia
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