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Diabetes insipidus - nephrogenic

Overview Symptoms Treatment Prevention
Alternative Names:
Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus;
Symptoms:
  • Excessive thirst (may be intense or uncontrollable, with a craving for ice water)
  • Excessive urine volume (may exceed 3 to 15 liters per day)
Inadequate fluid consumption can result in:
  • Dehydration
    • Dry skin
    • Dry mucous membranes
    • Sunken appearance to eyes
    • Sunken fontanelles (soft spot) in infants
  • Fatigue, lethargy
  • Headache
  • Irritability
  • Low body temperature
  • Muscle pains
  • Rapid heart rate
  • Weight loss
Signs and tests:
Examination may indicate dehydration and/or shock if fluid intake is inadequate. The pulse rate may be rapid, with a low blood pressure present. The most significant indication of diabetes insipidus is persistent high urine output regardless of fluid intake.

Signs associated with high urine output are:
  • High serum osmolality
  • Low urine osmolality
  • Normal or high ADH levels
  • The kidneys not making a more concentrated urine when the person is given ADH

This disease may also alter the results of the following tests:

Male urinary system
Male urinary system
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