| Alternative Names:
|
| Nephrogenic diabetes insipidus; Acquired nephrogenic diabetes insipidus; |
| Symptoms:
|
- Excessive thirst (may be intense or uncontrollable, with a craving for ice water)
- Excessive urine volume (may exceed 3 to 15 liters per day)
Inadequate fluid consumption can result in:
- Dehydration
- Dry skin
- Dry mucous membranes
- Sunken appearance to eyes
- Sunken fontanelles (soft spot) in infants
- Fatigue, lethargy
- Headache
- Irritability
- Low body temperature
- Muscle pains
- Rapid heart rate
- Weight loss
|
| Signs and tests:
|
Examination may indicate dehydration and/or shock if fluid intake is inadequate. The pulse rate may be rapid, with a low blood pressure present. The most significant indication of diabetes insipidus is persistent high urine output regardless of fluid intake.
Signs associated with high urine output are:
- High serum osmolality
- Low urine osmolality
- Normal or high ADH levels
- The kidneys not making a more concentrated urine when the person is given ADH
This disease may also alter the results of the following tests: |