Health Topics A-Z

  1. Home
  2. Health
  3. Health Topics A-Z

From About.com

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

ENCYCLOPEDIA INDEX
Injury Disease Nutrition Poison Symptoms Surgery Test Special Topic
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

AIDS

Overview Symptoms Treatment Prevention
Alternative Names:
Acquired immune deficiency syndrome
Treatment:

There is no cure for AIDS at this time. However, several treatments are available that can delay the progression of disease for many years and improve the quality of life of those who have developed symptoms.

Antiviral therapy suppresses the replication of the HIV virus in the body. A combination of several antiretroviral agents, termed Highly Active Anti-Retroviral Therapy (HAART), has been highly effective in reducing the number of HIV particles in the blood stream, as measured by a blood test called the viral load. This can help the immune system bounce back for a while and improve T-cell counts.

Although this is not a cure for HIV, and people on HAART with suppressed levels of HIV can still transmit the virus to others through sex or sharing of needles, the treatment shows great promise.

There is good evidence that if the levels of HIV remain suppressed and the CD4 count remains high (above 200), that life and quality of life can be significantly prolonged and improved. However, HIV tends to become resistant in patients who do not take their medications on schedule every day. Also, certain strains of HIV mutate easily and may become resistant to HAART especially quickly.

Genetic tests are now available to determine whether a particular strain is resistant to a particular drug -- these may be useful in determining the best drug combination and adjusting it if it starts to fail.

When HIV becomes resistant to HAART, salvage therapy is required to try to suppress the resistant strain of HIV. Different combinations of medications are used to try to reduce viral load. This is often not successful, unfortunately, and the patient will usually develop AIDS and its complications.

Treatment with HAART is not without complications. HAART is a collection of different medications, each with its own side effect profile. Some common side effects are nausea, headache, weakness, malaise, and fat accumulation on the back and abdomen ("buffalo hump," lipodystrophy). When used long-term, these medications may increase the risk of heart attack by affecting fat metabolism.

Any doctor prescribing HAART should carefully follow the patient for possible side effects associated with the combination of medications being taken. In addition, routine blood tests measuring CD4 counts and HIV viral load (a blood test that measures how much virus is in the blood) should be taken every three to four months. The goal is to get the CD4 count as close to normal as possible, and to suppress the HIV viral load to an undetectable level.

Other antiviral agents are in investigational stages and many new drugs are in the pipeline. Growth factors that stimulate cell growth, such as Epogen (erthythropoetin) and G-CSF are sometimes used to treat anemia and low white blood cell counts associated with AIDS.

Medications are also used to prevent opportunistic infections (such as Pneumocystis carinii pneumonia) and can keep AIDS patients healthier for longer periods of time. Opportunistic infections are treated as they occur.

Support Groups:

Joining support groups where members share common experiences and problems can often help the emotional stress of devastating illnesses. See AIDS - support group.

Expectations (prognosis):

At the present time, there is no cure for AIDS. It has proven to be a universally fatal illness. In the U.S., most patients survive many years following diagnosis because of the availability of the HAART treatment. HAART has dramatically increased the time from diagnosis to death, and research continues in drug treatments and vaccine development.

Complications:

When a patient is infected with HIV, the virus slowly begins to destroy that patient's immune system. How fast this occurs differs in each individual. Treatment with HAART can help slow and even halt the destruction of the immune system.

However, once the immune system is severely damaged, that patient is said to have developed AIDS, and is now susceptible to infections and cancers that most healthy adults would not get.

Calling your health care provider:

Call for an appointment with your health care provider if you have any of the risk factors for HIV infection, or if symptoms of AIDS are present. By law, AIDS testing must be kept confidential. Your health care provider will review results of your testing with you.

Tuberculosis in the lung
Tuberculosis in the lung
Kaposi's sarcoma - lesion on the foot
Kaposi's sarcoma - lesion on the foot
AIDS
AIDS
STDs and ecological niches
STDs and ecological niches
HIV
HIV
Primary HIV infection
Primary HIV infection
Canker sore (aphthous ulcer)
Canker sore (aphthous ulcer)
Mycobacterium marinum infection on the hand
Mycobacterium marinum infection on the hand
Dermatitis, seborrheic - close-up
Dermatitis, seborrheic - close-up
Dermatitis, seborrheic on the face
Dermatitis, seborrheic on the face
Histoplasmosis, disseminated in HIV patient
Histoplasmosis, disseminated in HIV patient
Molluscum on the chest
Molluscum on the chest
Kaposi's sarcoma on the back
Kaposi's sarcoma on the back
Kaposi's sarcoma - close-up
Kaposi's sarcoma - close-up
Kaposi's sarcoma on the thigh
Kaposi's sarcoma on the thigh
Kaposi's sarcoma - perianal
Kaposi's sarcoma - perianal
Molluscum contagiosum on the face
Molluscum contagiosum on the face
Herpes zoster (shingles), disseminated
Herpes zoster (shingles), disseminated
Antibodies
Antibodies
adam.com

Explore Health Topics A-Z

About.com Special Features

Do I Have Allergies?

Are your symptoms merely irritating, or could they be a sign of allergies? More >

Preventing Headaches

The best way to treat a headache is to prevent it. Learn how. More >

Health Topics A-Z

  1. Home
  2. Health
  3. Health Topics A-Z

©2009 About.com, a part of The New York Times Company.

All rights reserved.