People with recurrent outbreaks of oral thrush, or those who are at very high risk for development of the disorder, may be given prophylactic (preventive) antifungal medications. If an infant who is breast feeding has oral thrush, the mother also should use a topical antifungal medication on her nipples to prevent continuous spread to the infant.

In bottle-fed babies, discard the nipples and buy new ones as the babies mouth begins to clear because the fungus may get into the nipples and can not be easily eradicated.