Symptoms may be decreased somewhat with radiation therapy or corticosteroid injections into the fibrous band of tissue. Verapamil, an oral medication used for high blood pressure, has recently been shown to improve the disease, and has been approved for use in treating Peyronie's.

If medical therapy fails and intercourse is not possible because of the curvature of the penis, surgery may be performed to correct the curvature. Because of the risk that this procedure will cause impotence, it is only performed if intercourse is impossible.

The condition is typically progressive and leads to inability to have intercourse. The disease is also associated with development of impotence.

The condition may make intercourse difficult, painful, or impossible. Surgical correction may also lead to impotence.

Call your health care provider if symptoms indicating curvature of the penis occur, particularly if erections are painful.