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Gestational trophoblastic disease

Overview Symptoms Treatment Prevention
Alternative Names:
Chorioblastoma; Choriocarcinoma; Trophoblastic tumor; Chorioepithelioma; Invasive/malignant mole; Gestational trophoblastic neoplasia
Symptoms:

A possible symptom is continued vaginal bleeding in a woman with a recent history of hydatidiform mole, abortion, or term pregnancy.

Additional symptoms that may be associated with this disease include:

  • Irregular vaginal bleeding
  • Theca lutein cysts on the ovaries
  • Uneven enlargement of the uterus
  • Persistently elevated HCG (pregnancy hormone) levels
  • Pain
  • Symptoms related to the disease spreading to other organs (e.g., lungs, liver, brain)
Signs and tests:
A pelvic examination may reveal continued uterine enlargement or a tumor. These conditions may be felt within the genito-urinary tract.

Tests include:
  • Quantitative serum HCG (blood test to confirm pregnancy)
  • CT scan to detect potential metastatic tumor in any organ
  • Chest X-ray
Note: These signs and tests apply to women with a recent history of hydatidiform mole, abortion, or term pregnancy.
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