LDL test
Definition
The LDL test measures how much low-density lipoprotein (LDL) you have in your blood. LDL is a type of cholesterol. Too much LDL in the blood can clog arteries.
See also:
Alternative Names
Low-density lipoprotein testHow the Test is Performed
Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.
Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.
How to Prepare for the Test
You may be told not to eat or drink anything for 9 - 12 hours before the test.
The health care provider may tell you to stop taking certain drugs before the procedure. Drugs that can affect the LDL test include aspirin, birth control pills, phenothiazines, corticosteroids, and sulfonamides.
How the Test Will Feel
When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the Test is Performed
This test is usually done to determine your risk for heart disease. The LDL test is usually done as part of a lipid analysis, which also checks for total cholesterol, HDL, and triglycerides.
LDL is carries cholesterol to various tissues throughout the body. Too much LDL, commonly called "bad cholesterol," can lead to cardiovascular disease.
According to the National Heart, Lung, and Blood Institute, the lower your LDL, the lower your risk for heart disease or stroke.
A healthy LDL level is one that falls in the optimal or near-optimal range.
- Optimal: Less than 100 mg/dL (less than 70mg/dL for persons with a history of heart disease or those at very high risk for atherosclerotic disease)
- Near Optimal: 100-129 mg/dL
- Borderline High: 130-159 mg/dL
- High: 160-189 mg/dL
- Very High: 190 mg/dL and higher
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
High levels of LDL may be associated with:
- Increased risk of atherosclerotic heart disease
- Familial hyperlipoproteinemia
- Malabsorption (inadequate absorption of nutrients from the intestinal tract)
- Malnutrition
Risks
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
References
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486-2497.Reviewed By: Glenn Gandelman, MD, MPH, Assistant Clinical Professor of Medicine, New York Medical College, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
