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Alzheimer's Disease

Description

An in-depth report on the causes, diagnosis, and treatment of Alzheimer's disease.

Symptoms

The early symptoms of Alzheimers disease (AD) may be overlooked because they resemble signs of natural aging. Still, older adults who begin to notice a persistent mild memory loss of recent events may have a condition called mild cognitive impairment (MCI). MCI is now believed to be a significant sign of early-stage Alzheimer's in older people. Studies now suggest that older individuals who experience such mild memory abnormalities convert to Alzheimer's disease at a rate of about 10% to 15% per year.

Early symptoms of Alzheimer's disease include the following:

  • Forgetfulness.
  • Loss of concentration.
  • Unexplained weight loss.
  • Motor problems, including mild difficulties in walking.
  • Incontinence
  • Changes in sexuality;
  • Psychiatric symptoms (depression, apathy, irritability). Such symptoms occur in about half of patients, and in most cases they occur very early on.

Between 40% and 60% of patients with late-onset Alzheimer's disease suffer from psychotic symptoms, which may include hallucinations, delusions, and dramatic verbal, emotional or physical outbursts. This is a severe form of Alzheimer's disease, possibly with a genetic basis, that has a more rapid and aggressive course.

It should be noted that many medical and psychological conditions can produce Alzheimer-like symptoms. About 20% of suspected Alzheimers cases, in fact, turn out to be some other disorder, half of which are potentially treatable or controllable.

DIFFERENCES BETWEEN NORMAL SIGNS OF AGING AND DEMENTIA

NORMAL

DEMENTIA

Early Signs of Alzheimer's Disease

Memory and Concentration

Periodic minor memory lapses or forgetfulness of part of an experience.

Occasional lapses in attention or lapses in attention or concentration.

Misplacement of important items.

Confusion about how to perform simple tasks.

Trouble with simple arithmetic problems.

Difficulty making routine decisions.

Confusion about month or season.

Mood and Behavior

Temporary sadness or anxiety based on appropriate and specific cause.

Changing interests.

Increasingly cautious behavior.

Unpredictable mood changes.

Increasing loss of outside interests.

Depression, anger, or confusion in response to change.

Denial of symptoms.

Later Signs of Alzheimer's Disease

Language and Speech.

Unimpaired language skills.

Difficulty completing sentences or finding the right words.

Inability to understand the meaning of words.

Reduced and/or irrelevant conversation.

Movement/ Coordination

Increasing caution in movement.

Slower reaction times.

Visibly impaired movement or coordination, including slowing of movements, halting gait, and reduced sense of balance.

Other Symptoms

Normal sense of smell. No abnormal weight changes in either men or women.

Impaired sense of smell. Severe weight loss, particularly in female patients.

Source of most of the data: Alzheimer's Disease: Early Warning Signs and Diagnostic Resources. The Junior League of NYC, Inc, 1988

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