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Infertility In Women

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of female infertility.

Alternative Names

Pelvic Inflammatory Disease; Polycystic Ovaries

Lifestyle Changes

Although there are no dietary or nutritional cures for infertility, a healthy lifestyle is important. Ovulatory problems are reversible by changing behavioral patterns. Such conditions include:

  • Maintain a healthy weight. Women who are either over- or underweight are at risk for fertility failure, including a lower chance for achieving success with fertility procedures. Everyone should have a diet rich in fresh fruits and vegetables, and whole grains and that is also low in saturated fats.
  • Stop smoking. Smoking increases the risk for infertility in both men and women, and poses a future health risk for the mother and infant. Everyone should quit.
  • Avoid caffeine and alcohol.
  • Avoid excessive exercise if it causes menstrual irregularity. It should be strongly noted that moderate and regular exercise is essential for good health. Few women exercise to the extent that their periods are affected. For those that do, one study found that simply adding calories can restore menstruation in many cases. Competitive athletes, then, may not have to stop exercising to restore fertility, although more research is needed to confirm this.
  • Don't use electric blankets. In one study, a 74% higher incidence of spontaneous abortion was associated with using an electric blanket during the month of conception. There was no association with heated waterbeds or electromagnetic waves.
  • Avoid any unnecessary medications.

There is no evidence of harm to a developing fetus from low exposure to microwaves or electromagnetic waves. Women who remain anxious may derive comfort by avoiding some of these devices (such as cellular phones or electric blankets) and remaining a foot or so away from others (such as computers or microwave ovens).

Planning Sexual Activity and Monitoring Basal Body Temperature

Both male and female hormone levels fluctuate according to the time of day and they also vary from day to day and month to month. Some timing tips might be helpful.

Male Hormone Levels and Sexual Activity. Male hormone levels are highest in the morning. (Sexual interest also tends to be higher in the morning.) In one study of men, their sexual activity was highest in October, when conception rates were also high.

Fertility and Seasonal Changes. Different studies have reported higher sperm counts in the winter than in the summer. For women, fertility rates as measured by treatment success are highest in months when days are longest.

Monitoring Basal Body Temperature. To determine the most likely time of ovulation and therefore the time of fertility, a woman is instructed to take her body temperature, called her basal body temperature. This is the bodys temperature as it rises and falls in accord with hormonal fluctuations.

  • Each morning before rising, the woman takes her temperature with a specialized basal body thermometer and marks the result on a graph-paper chart. (Of interest is a wrist watch-like device under investigation that measures skin changes to predict ovulation.)
  • The woman also notes the days of menstruation and sexual activity.
  • The so-called "fertile window" is six days long and starts five days before ovulation and ends the day of ovulation.
  • The chances for fertility are considered to be highest between days 10 and 17 in the menstrual cycle (with day 1 being the first day of the period and ovulation occurring about two weeks later). It should be noted, however, that a 2000 study reported that only 30% of women were fertile within the period of time. In the study, women had a 10% chance of ovulating on each day between day 6 and 21. Researchers who conducted the study suggested that each woman track the length of her cycle, which in the general population of women actually runs between 19 and 60 days. A long cycle, for example, suggests a delayed ovulation date.
  • Immediately after ovulation the body temperature increases sharply in about 80% of cases. (Some women can be ovulating normally yet not show this temperature pattern.)

By studying the temperature patterns after a few months, couples can begin to anticipate ovulation and plan their sexual activity accordingly. Couples must try to avoid becoming fixated on the chart, however, in scheduling their sexual activity. Spontaneity can be lost, and the stress on the relationship can be quite severe, possibly impeding fertility.

Hormone Monitoring Systems. A device called a saliva fertility monitor (Fertility Tracker) uses a microscope to view slides containing saliva and monitors estrogen levels. Home test kits that monitor reproductive hormone levels in the urine (e.g., ClearBlue) are also available. They are less costly than the saliva test but are messier. Monitoring hormones levels helps to determine when a woman is ovulating.

Frequency of Intercourse. The question of how often a couple should have intercourse is in debate. Some experts say that having sex more than two days a week adds no benefits. And, in fact, frequent sexual activity lowers sperm count per ejaculation. Some studies have indicated, however, that having intercourse every day, or even several times a day, before and during ovulation improves pregnancy rates. Although sperm count per ejaculation is low, a constantly replenished semen supply is more likely to result in a fertilized egg.

Planning for Stress and Depression

The fertility process is a roller coaster of emotions that are present throughout and in both failure and success. There are almost no sure ways to predict which couples will eventually conceive. Some couples with multiple problems will overcome great odds, while other, seemingly fertile, couples fail to conceive. Many of the new treatments are remarkable, but a live birth is never guaranteed. The emotional burden on the couple is considerable and some planning is helpful.

Planning for Emotional Turmoil.

  • Decide in advance how many and what kind of procedures will be emotionally and financially acceptable and attempt to determine a final limit. Fertility treatments are expensive. A successful pregnancy often depends on repeated attempts and the average cost is about $40,000. As of 2002, eight states required partial or full insurance coverage. (Some couples become addicted to treatment, and continue with fertility procedures until they are emotionally and financially drained.)
  • Determine alternatives (adoption, donor sperm or egg, or having no children) as early as possible in the fertility process. This can reduce anxiety during treatments and feelings of hopelessness in case conception does not occur.

Managing Emotional Stress During the Process. Managing negative emotions can be viewed as important as medical treatment. A 2001 study, for example, reported that women undergoing fertility treatments who had the highest levels of stress were 93% less likely to deliver a baby after five years compared to the most relaxed women. Women who were optimistic had a much higher likelihood of pregnancy. Other studies have also reported a significant association between psychologic factors, particularly anxiety, and fertility treatment failure. The following are some ways women reduce stress while trying to conceive:

  • Talking to ones spouse, family, and friends is very beneficial. The best support comes from the spouse. Studies suggest that a positive attitude on the husband's part is essential for enabling his wife to deal effectively with either the success or failure of fertility treatments. It should be noted, however, that men and women may cope differently with the stress and each should understand the other's special needs. Women tend to want greater personal space and also to want to share the burden with their husbands. Men tend to cope by seeking to improve themselves (for example being strong, or being the "best").
  • Almost half of women seeking fertility treatments practice good-luck rituals, including prayer and wearing charms or special jewelry. No evidence exists that these talismans increase fertility, but they may help reduce anxiety and enhance a sense of control.
  • Cognitive-behavioral therapy, which uses methods that include relaxation training and stress-management, have been associated with higher pregnancy rates. (In one study, 42% became pregnant without medical intervention.)
  • Acupuncture may help some women. Some evidence suggests that this alternative treatment has some beneficial effects on chemicals in the brain involved with stress and reproduction. In one intriguing study, women who were given acupuncture achieved significantly higher success rates during fertility treatments (42.5%) than those who were not given it (26.3%). Studies are needed to confirm any benefits.
  • Attending support groups or counseling services for help before and after treatment helps many women endure the process and ease the grief should treatment fail. One study indicated that pregnancy rates were twice as high in women who coped with their depression by reaching out to others rather than repressing guilt or rage. (These results held only in cases in which women, not their mates, were infertile.)

Managing the Emotional Effects of the Outcome. After enduring the process, the couple must face the outcome, and even a positive outcome has emotional repercussions.

  • Effects of Failure. Needless to say, the emotional stress of failure can be devastating even on the most loving and affectionate relationships and even in those who have prepared for the possibility of failure. Neither the male or female partner should hesitate to seek professional help if the emotional burdens are too heavy.
  • Effects of Genetic Testing. As advanced technologies allow testing and greater genetic information at the earliest stage, potential parents will have to learn to deal with the uncertainties of possible chromosomal abnormalities, which may or may not be significant.
  • Effects of Successful Treatments. Some studies have indicated that even if successful, some women experience higher stress and fear of failure during pregnancy. According to one 2000 study, however, women who achieved pregnancy using fertility treatments felt increasingly better and had higher self esteem and less anxiety as the pregnancy progressed than women whose pregnancies were not due to medical intervention.
  • Effects of Multiple Births. A successful pregnancy that results in a multiple birth introduces new complexities and emotional problems. One study reported a very high rate of depression in women with triplets, particularly if they had little help from others, and especially if their husbands weren't involved.
  • Effects on Parenting. Once the fertility treatment-assisted child arrives, parents (both men and women) are more likely to be anxious and to have less confidence than those who conceive naturally.
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