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Psoriasis

Description

An in-depth report on the causes, diagnosis, treatment, and prevention of psoriasis.

Alternative Names

PUVA therapy

Managing Psoriasis

Although sunburn carries a risk for skin cancer and may actually exacerbate psoriasis, regular exposure to the sun helps clear psoriasis in people with mild to moderate conditions. Experts advise covering non-affected areas with clothing or sunscreen and sun bathing only until the skin starts to tan. Vacations in sunny areas, such as Hawaii or the Caribbean, can offer relief. For those who can afford it, a prolonged stay of several weeks at the Dead Sea in Israel has proven to significantly improve or clear 88% of those with psoriasis. The region offers a unique combination of intense but naturally filtered UVA radiation combined with minerals and salts from the sea.

Emotional Support

Because of the association between negative emotions and psoriatic flare-ups, relaxation and anti-stress techniques may be helpful. Many are available. The following are some studies suggesting that emotional support may have an impact on psoriasis:

  • One study investigated patients with psoriasis who discussed with a psychiatrist any traumatic or other intense event that occurred when the skin condition appeared. In the study, 68% of patients recalled such an event and 62% experienced significant improvement after the talk session.
  • Another study reported that patients treated with antidepressants along with topical corticosteroids for psoriasis experienced greater skin improvement than those who took the steroid alone.
  • Hypnosis aimed at reducing stress may allay symptoms, according to a small 1999 study.

Treating Dry Skin

If skin becomes dry and itchy, the patient may try the following:

  • Soak in a warm bath for about 15 minutes.
  • Afterward, apply salicylic acid first, which removes scaly skin and may promote the penetration of both moisturizers and topical prescription medications.
  • Then, apply a thick moisturizer or emollient, such as Vaseline, Cetaphil cream, or Eucerin cream. (Lotions are not adequate moisturizers.)
  • Special gloves made of Gore-Tex (DermaPore) may be worn at night over a thick moisturizer cream. These gloves are protective but also allow moisture to escape.

Some experts suggest that many common moisturizers may actually increase water loss in psoriasis, but studies are needed to confirm this. In the meantime, if moisturizers help relieve the condition, then patients should use them.

Alleviating Itching and Irritation

Capsaicin (Zostrix) is an ointment prepared from the active ingredient in hot chili peppers. It is used to relieve arthritic pain and may help relieve psoriatic itching. Capsaicin should be handled using a glove and applied to affected areas three or four times daily. The patient will usually experience a burning sensation when the drug is first applied, but this sensation diminishes with use.

Dietary Factors

Folic Acid. Patients should be sure they get enough of the B vitamin folate (called folic acid in supplement form). Folate-rich foods include liver, asparagus, fruits, green leafy vegetables, dried beans and peas, orange juice, and yeast. Many breads and other commercial grain products are now enriched with folic acid.

Omega-3 Fatty Acids. Omega-3 fatty acids, particularly those found in some fish oil, have anti-inflammatory properties that may benefit some patients with psoriasis and other autoimmune conditions.

Alternative Remedies

Patients with persistent psoriasis may be tempted to try alternative or untested treatments, including herbs and other nontraditional therapies. A number of traditional remedies include various herbs, but to date no clinical studies have been reported on these substances. No one should use any so-called natural or unproven therapies without consulting their physicians to be sure such treatment is not harmful and does not interfere with any standard medications being taken.

Warnings on Alternative and So-Called Natural Remedies

Alternative or natural remedies are not regulated and their quality is not publicly controlled. In addition, any substance that can affect the body's chemistry can, like any drug, produce side effects that may be harmful. Even if studies report positive benefits from herbal remedies, the compounds used in such studies are, in most cases, not what are being marketed to the public.

There have been a number of reported cases of serious and even lethal side effects from herbal products. In addition, some so-called natural remedies were found to contain standard prescription medications. Most reported problems occur in herbal remedies imported from Asia, with one study reporting a significant percentage of such remedies containing toxic metals.

Of note for patients with psoriasis:

  • Zinc pyrithione is sometimes used, but its effectiveness is doubtful. A number of so-called natural psoriasis products (Skin-Cap, Blue Cap, Miralex) that contain this compound, however, also contain prescription-strength corticosteroids. Such steroids have the same side effects as those in standard psoriasis agents. These products have been banned in the US and Canada, but similar untested medications are available over the Internet.
  • Gotu Kola (centella asiatica) is sometimes used as a topical application for psoriasis. The agent in oral form has serious side effects, however, including increasing the risk for miscarriage in pregnant women.

The following website is building a database of natural remedy brands that it tests and rates. Not all are available yet (www.consumerlab.com).

The Food and Drug Administration has a program called MEDWATCH for people to report adverse reactions to drugs, herbal remedies, supplements and vitamins (800-332-1088).

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